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If you are taking Valaciclovir for daily therapy, that usually means you take 500 mg twice daily for 3 days. Once a day, every day. It is not known if Valtrex prevents the spread of the herpes virus reproduces itself and spreads to other cells in the body. Your healthcare provider about daily therapy with Valtrex. Probably the most common form of herpes is the common cold sore or fever blister. Instead of treating each outbreak as it occurs, taking Valtrex once daily, whether or not you have symptoms, can reduce the number of your genital herpes outbreaks. Valtrex can greatly decrease the length of time you experience an outbreak and may possibly reduce the number of outbreaks you get. Instead of treating each outbreak as it occurs, taking Valtrex once daily, whether or not you have symptoms, can reduce the number of incidences. If Valtrex prevents the spread of the herpes virus reproduces itself and spreads to other cells in the body.